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What is Tadalafil (Cialis)

Many people freak out on Viagra, while some go totally gung ho on Cialis; may be it is all about the basic human taste, you love ice-cream, well, and I'd rather munch those cookies. Tadalafil is contraindicated in men for whom sexual intercourse is inadvisable due to unstable cardiovascular disease (e.g. patients with unstable angina and severe congestive heart failure) (see Section 4.4 Special Warnings and Precautions for Use).
The use of ED drugs is not recommended in men who have a recent history of stroke or myocardial infarction (within the last 6-8 weeks), or who have significantly low 犀利士網購 blood pressure, uncontrolled high blood pressure, unstable angina, severe cardiac failure, severe liver impairment or end-stage kidney disease requiring dialysis.

Individuals who are taking medications that increase the blood levels of tadalafil should not exceed a total dose of 10 mg in 72 hours (See drug interactions ). For once daily use without regard to sexual activity, the recommended dose is 2.5 to 5 mg daily.
In part C (N=24), subjects were titrated to doxazosin 8 mg administered daily at 8 a.m. In this part, tadalafil or placebo were administered at either 8 a.m. or 8 p.m. Blood pressure was measured by ABPM every 15 to 30 minutes for up to 36 hours after tadalafil or placebo.

Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells.
Therefore, in all 7 primary efficacy and safety studies, CIALIS showed statistically significant improvement in patients' ability to achieve an erection sufficient for vaginal penetration and to maintain the erection long enough for successful intercourse, as measured by the IIEF questionnaire and by SEP diaries.
The effect of a single 100-mg dose of tadalafil on the QT interval was evaluated at the time of peak tadalafil concentration in a randomized, double-blinded, placebo, and active (intravenous ibutilide) -controlled crossover study in 90 healthy males aged 18 to 53 years.

In the long-term open label extension phase of the controlled study LVHG, in which patients received Cialis 5 mg for up to 1 year after the 12 week double blind treatment period, the improvement in total IPSS induced by tadalafil at week 12 of double blind treatment was maintained over 1 year.
Prior to initiating treatment with tadalafil for lower urinary tract symptoms associated with benign prostatic hyperplasia, a medical history and physical examination should be undertaken to rule out the presence of carcinoma of the prostate as well as other potential underlying causes of urinary symptoms and the patient should be carefully assessed for cardiovascular conditions.

Dizziness, stomach ache, feeling sick, being sick (vomiting), reflux, blurred vision, eye pain, difficulty in breathing, presence of blood in urine, prolonged erection, pounding heartbeat sensation, a fast heart rate, high blood pressure, low blood pressure, nose bleeds, ringing in the ears, swelling of the hands, feet or ankles and feeling tired.
Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and the smooth muscle of the corpus cavernosum This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cyclic guanosine monophosphate (more commonly known as cyclic GMP or cGMP) in smooth muscle cells.

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